Palladium may refer to:
- Palladium Ore, an ore made into Palladium Bars.
- Palladium Bar, a bar made from Palladium Ore.
- Palladium armor, an armor set created with Palladium Bars.
- Palladium Column, a building block made with Palladium Ore.
- Palladium Column Wall, a wall made of Palladium Columns.
- Palladium Pickaxe and Palladium Drill, functionally identical tools made from Palladium Bars.
- Palladium Sword and Palladium Pike, sword and spear weapons, respectively, made from Palladium Bars.
- Palladium Repeater, a bow-type weapon made from Palladium Bars.
Palladium may be mistaken with:
- Paladin, a mini-boss found in the post-Plantera Dungeon.
- Paladin's Hammer, a powerful melee weapon dropped by Paladin.
- Paladin's Shield, a defensive accessory dropped by Paladin which grants defense and protects teammates from damage.