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From Terraria Wiki
The Bloody Spine is a consumable item used to summon the Brain of Cthulhu Boss while within the Crimson. Attempting to use it outside the Crimson will have no effect and will not consume the item.
Console and Mobile versions[edit | edit source]
- Although the Corruption is equivalent to the Crimson, using the Bloody Spine in the Corruption will not do anything.
- It is however still possible to summon the Brain of Cthulhu in a world that generated Corruption by artificially creating a Crimson biome (with Crimstone blocks from another world) and then using the Bloody Spine within that.